Future Prospects for Neisseria gonorrhoeae Treatment
نویسندگان
چکیده
منابع مشابه
Optimizing Treatment of Antimicrobial-resistant Neisseria gonorrhoeae
The increasing prevalence of ciprofloxacin-resistant Neisseria gonorrhoeae has required replacing inexpensive oral ciprofloxacin treatment with more expensive injectable ceftriaxone. Further, monitoring antimicrobial resistance requires culture testing, but nonculture gonorrhea tests are rapidly replacing culture. Since the strategies were similar in effectiveness (> 99%), we evaluated, from th...
متن کاملDiagnosis and treatment of Neisseria gonorrhoeae infections.
The most common site of Neisseria gonorrhoeae infection is the urogenital tract. Men with this infection may experience dysuria with penile discharge, and women may have mild vaginal mucopurulent discharge, severe pelvic pain, or no symptoms. Other N. gonorrhoeae infections include anorectal, conjunctival, pharyngeal, and ovarian/uterine. Infections that occur in the neonatal period may cause o...
متن کاملNeisseria gonorrhoeae
Two fi-lactamase-producing strains of Neisseria gonorrhoeae were studied. The substrate profile, molecular weight, and isoelectric point of their ,8-lactamases were similar to those of the TEM-1 enzyme produced by many gram-negative bacilli. The gonococcal f8-lactamase was cell bound during exponential growth and was most likely located in the periplasm. Penicillin hydrolysis was efficient in i...
متن کاملNeisseria gonorrhoeae
Expression of Type IV pili by the bacteria! pathogen Neisseria gonorrhoeae appears to be essential for colonization of the human host. Several N. gonorrhoeae gene products have been recently identified which bear homology to proteins invoived in pilus assembly and protein export in other bacterial systems. We report here the isolation and characterization of transposon insertion mutants in N. g...
متن کاملQuinolones for the Treatment of Neisseria Gonorrhoeae and Chlamydia Trachomatis
The most commonly sexually transmitted bacteria are Neisseria gonorrhoeae and Chlamydia trachomatis. The quinolones ofloxacin and ciprofloxacin have been shown to have activity against both of these bacteria in vitro and in vivo. Ofloxacin is particularly well suited for the treatment of N. gonorrhoeae and C. trachomatis cervical infection, which can be considered the earliest manifestation of ...
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ژورنال
عنوان ژورنال: Antibiotics
سال: 2018
ISSN: 2079-6382
DOI: 10.3390/antibiotics7020049